Wellbutrin (Bupropion hydrochloride) for Narcolepsy | MyNarcolepsyTeam

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Wellbutrin is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat major depressive disorder. Wellbutrin is sometimes prescribed off-label to treat narcolepsy. Wellbutrin is also referred to by its drug name, bupropion hydrochloride.

Wellbutrin is an atypical antidepressant. It is known as a norepinephrine and dopamine reuptake inhibitor. Wellbutrin is believed to work by keeping norepinephrine and dopamine available in the brain for longer. These neurotransmitters are thought to increase attention and wakefulness, which can reduce symptoms of narcolepsy.

How do I take it?
Prescribing information states that Wellbutrin is taken by mouth two or three times a day.

Wellbutrin comes in tablet form. It should be taken exactly as prescribed by a physician.

Side effects
The FDA-approved label for Wellbutrin lists common side effects including agitation, dry mouth, nausea, vomiting, headache or migraine, constipation, sweating, tremor, insomnia, blurry vision, racing heart rate or other heart problems, confusion, rash, hearing disturbances, and hostility.

Rare but serious side effects listed for Wellbutrin include suicidal thoughts, worsened depression, seizures, psychosis, mania, high blood pressure, and glaucoma.

For more details about this treatment, visit:

Wellbutrin — RxList

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