Xyrem (Sodium oxybate) for Narcolepsy | MyNarcolepsyTeam

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Xyrem is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat cataplexy and excessive daytime sleepiness in people 7 years and older who have narcolepsy. Xyrem is also referred to by its drug name, sodium oxybate.

Xyrem belongs to a class of drugs called depressants. Xyrem is believed to work by increasing sleep quality at night to prevent sleep during the day.

How do I take it?
Prescribing information states that Xyrem is taken by mouth in two doses at nighttime.

Xyrem comes in an oral solution.

Side effects
The FDA-approved label for Xyrem lists common side effects including nausea, dizziness, vomiting, drowsiness, involuntary urination, and tremors.

Rare but serious side effects listed for Xyrem include central nervous system depression (which can slow breathing and heart rate), depression, suicidality, confusion, anxiety, and sleep walking.

For more details about this treatment, visit:

Xyrem — RxList

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