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Real members of MyNarcolepsyTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is there any chance that Wakix and or Adderal cause vertigo in high altitudes?

A MyNarcolepsyTeam Member asked a question 💭
Warrenton, VA

There have been times where I experience vertigo or having the sensation of lightheaded, dizziness and loss of balance while inflight as a working cabin attendant. I’ve noticed that it’s more prevalent when I’ve taken my medication a few hours prior to departure as opposed to taking it inflight after reaching cruising altitude.

August 22
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MyNarcolepsyTeam

That's a really important observation, especially given your role as a cabin attendant. Both Wakix (pitolisant) and Adderall can have side effects that may overlap with altitude-related symptoms. Wakix's known side effects include nausea and anxiety, while Adderall can cause dizziness and changes in blood pressure.

At Show Full Answer

That's a really important observation, especially given your role as a cabin attendant. Both Wakix (pitolisant) and Adderall can have side effects that may overlap with altitude-related symptoms. Wakix's known side effects include nausea and anxiety, while Adderall can cause dizziness and changes in blood pressure.

At altitude, cabin pressure is lower than at sea level, which can affect how your body absorbs and responds to medications. Taking stimulant-type medications before a pressurized environment could potentially amplify these effects. Here are some key points worth discussing with your doctor:

- Timing of medication — Your observation about timing is clinically relevant and worth documenting carefully before your appointment
- Blood pressure changes — Stimulant medications can affect circulation, which altitude may further influence
- Hydration — Cabin environments are very dry, and dehydration can worsen dizziness alongside medication effects
- Dosage adjustments — Your doctor may be able to suggest a modified schedule suited to your flight duties

Given the safety-critical nature of your job, please don't adjust your medication timing or dosage without speaking to your healthcare provider first. This pattern you've noticed is genuinely worth flagging — it's exactly the kind of real-world detail that helps doctors fine-tune treatment plans.

August 22

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